Term Information

Data health 
Accession
GO:0001228
Name
DNA-binding transcription activator activity, RNA polymerase II-specific
Ontology
molecular_function
Synonyms
RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II transcriptional activator activity, copper ion regulated proximal promoter sequence-specific DNA binding, RNA polymerase II transcriptional activator activity, metal ion regulated core promoter proximal region sequence-specific binding, RNA polymerase II transcriptional activator activity, metal ion regulated proximal promoter sequence-specific DNA binding, RNA polymerase II transcriptional activator activity, zinc ion regulated core promoter proximal region sequence-specific binding, RNA polymerase II transcriptional activator activity, zinc ion regulated proximal promoter sequence-specific DNA binding, copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription, distal enhancer DNA-binding transcription activator activity, RNA polymerase II-specific, metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription, metal ion regulated sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific, sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in positive regulation of transcription, transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding, transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding, transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding, transcriptional activator activity, metal ion regulated sequence-specific DNA binding, zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription
Alternate IDs
GO:0001209, GO:0001205, GO:0001212, GO:0001213, GO:0001211, GO:0001077
Definition
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units. Source: GOC:txnOH-2018
Comment
Merged terms, see https://github.com/geneontology/go-ontology/issues/16152 and https://github.com/geneontology/go-ontology/issues/16534; changed term label and definition https://github.com/geneontology/go-ontology/issues/16131
History
See term history for GO:0001228 at QuickGO
Subset
None

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Parents of DNA-binding transcription activator activity, RNA polymerase II-specific (GO:0001228)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA-binding transcription activator activity, RNA polymerase II-specific [is_a relation] is_a  DNA-binding transcription activator activity (GO:0001216)
DNA-binding transcription activator activity, RNA polymerase II-specific [is_a relation] is_a  DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)
DNA-binding transcription activator activity, RNA polymerase II-specific [BFO:0000050 relation] BFO:0000050  positive regulation of transcription by RNA polymerase II (GO:0045944)
Children of DNA-binding transcription activator activity, RNA polymerase II-specific (GO:0001228)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ATF4-CREB1 transcription factor complex (GO:1990589) [RO:0002215 relation] RO:0002215  DNA-binding transcription activator activity, RNA polymerase II-specific
ATF1-ATF4 transcription factor complex (GO:1990590) [RO:0002215 relation] RO:0002215  DNA-binding transcription activator activity, RNA polymerase II-specific
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