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Term Information

Data health 
Accession
GO:0004407
Name
histone deacetylase activity
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes. Source: EC:3.5.1.98, PMID:9893272
Comment
None
History
See term history for GO:0004407 at QuickGO
Subset
None

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Graph of GO:0004407 from QuickGO

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Parents of histone deacetylase activity (GO:0004407)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
histone deacetylase activity [BFO:0000050 relation] BFO:0000050  histone deacetylation (GO:0016575)
histone deacetylase activity [is_a relation] is_a  protein deacetylase activity (GO:0033558)
histone deacetylase activity [is_a relation] is_a  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811)
Children of histone deacetylase activity (GO:0004407)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
histone deacetylase activity (H4-K16 specific) (GO:0034739) [is_a relation] is_a  histone deacetylase activity
histone deacetylase activity (H3-K14 specific) (GO:0031078) [is_a relation] is_a  histone deacetylase activity
NAD-independent histone deacetylase activity (GO:0045129) [is_a relation] is_a  histone deacetylase activity
histone deacetylase activity (H3-K4 specific) (GO:1990162) [is_a relation] is_a  histone deacetylase activity
histone deacetylase inhibitor activity (GO:0046811) [RO:0002212 relation] RO:0002212  histone deacetylase activity
NAD-dependent histone deacetylase activity (GO:0017136) [is_a relation] is_a  histone deacetylase activity
histone deacetylase regulator activity (GO:0035033) [RO:0002211 relation] RO:0002211  histone deacetylase activity
regulation of histone deacetylase activity (GO:1901725) [RO:0002211 relation] RO:0002211  histone deacetylase activity
positive regulation of histone deacetylase activity (GO:1901727) [RO:0002213 relation] RO:0002213  histone deacetylase activity
histone deacetylase activity (H3-K9 specific) (GO:0032129) [is_a relation] is_a  histone deacetylase activity
histone deacetylase complex (GO:0000118) [RO:0002215 relation] RO:0002215  histone deacetylase activity
negative regulation of histone deacetylase activity (GO:1901726) [RO:0002212 relation] RO:0002212  histone deacetylase activity