Term Information

Data health 
Accession
GO:0007189
Name
adenylate cyclase-activating G protein-coupled receptor signaling pathway
Ontology
biological_process
Synonyms
G protein signaling, adenylate cyclase activating pathway, G protein signaling, adenylyl cyclase activating pathway, G protein signalling, adenylate cyclase activating pathway, G protein signalling, adenylyl cyclase activating pathway, G-protein signaling, adenylate cyclase activating pathway, G-protein signaling, adenylyl cyclase activating pathway, G-protein signalling, adenylate cyclase activating pathway, G-protein signalling, adenylyl cyclase activating pathway, GPCR signaling pathway via activation of adenylate cyclase, GPCR signaling pathway via activation of adenylate cyclase activity, adenylate cyclase-activating GPCR signaling pathway, positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, activation of adenylate cyclase activity by G-protein signaling pathway, activation of adenylate cyclase activity involved in G-protein signaling, positive regulation of adenylate cyclase activity by G-protein signaling pathway, positive regulation of adenylate cyclase activity by G-protein signalling pathway
Alternate IDs
GO:0010579, GO:0010580
Definition
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation of adenylyl cyclase activity and a subsequent increase in the concentration of cyclic AMP (cAMP). Source: GOC:signaling, GOC:dph, GOC:tb, GOC:mah, ISBN:0815316194
Comment
This term can be used to annotate ligands, receptors and G-proteins that lead to activation of adenylate cyclase activity within a signaling pathway.
History
See term history for GO:0007189 at QuickGO
Subset
None

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Parents of adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0007189)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
adenylate cyclase-activating G protein-coupled receptor signaling pathway [is_a relation] is_a  adenylate cyclase-modulating G protein-coupled receptor signaling pathway (GO:0007188)
adenylate cyclase-activating G protein-coupled receptor signaling pathway [is_a relation] is_a  cAMP-mediated signaling (GO:0019933)
adenylate cyclase-activating G protein-coupled receptor signaling pathway [BFO:0000051 relation] BFO:0000051  activation of adenylate cyclase activity (GO:0007190)
Children of adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0007189)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
adenylate cyclase-activating adrenergic receptor signaling pathway (GO:0071880) [is_a relation] is_a  adenylate cyclase-activating G protein-coupled receptor signaling pathway
regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0106070) [RO:0002211 relation] RO:0002211  adenylate cyclase-activating G protein-coupled receptor signaling pathway
adenylate cyclase-activating serotonin receptor signaling pathway (GO:0007192) [is_a relation] is_a  adenylate cyclase-activating G protein-coupled receptor signaling pathway
adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway (GO:0010619) [is_a relation] is_a  adenylate cyclase-activating G protein-coupled receptor signaling pathway
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0106072) [RO:0002212 relation] RO:0002212  adenylate cyclase-activating G protein-coupled receptor signaling pathway
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0106071) [RO:0002213 relation] RO:0002213  adenylate cyclase-activating G protein-coupled receptor signaling pathway
adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) [is_a relation] is_a  adenylate cyclase-activating G protein-coupled receptor signaling pathway
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