Term Information

Data health 
Accession
GO:0071456
Name
cellular response to hypoxia
Ontology
biological_process
Synonyms
cellular response to hypoxic stress, cellular response to lowered oxygen tension
Alternate IDs
None
Definition
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. Source: GOC:mah
Comment
Note that this term should not be confused with 'cellular response to anoxia ; GO:0071454'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.
History
See term history for GO:0071456 at QuickGO
Subset
None

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Parents of cellular response to hypoxia (GO:0071456)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cellular response to hypoxia [is_a relation] is_a  response to hypoxia (GO:0001666)
cellular response to hypoxia [is_a relation] is_a  cellular response to stress (GO:0033554)
cellular response to hypoxia [is_a relation] is_a  cellular response to decreased oxygen levels (GO:0036294)
Children of cellular response to hypoxia (GO:0071456)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
intrinsic apoptotic signaling pathway in response to hypoxia (GO:1990144) [BFO:0000050 relation] BFO:0000050  cellular response to hypoxia
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia (GO:2000777) [BFO:0000050 relation] BFO:0000050  cellular response to hypoxia
negative regulation of cellular response to hypoxia (GO:1900038) [RO:0002212 relation] RO:0002212  cellular response to hypoxia
hypoxia-inducible factor-1alpha signaling pathway (GO:0097411) [BFO:0000050 relation] BFO:0000050  cellular response to hypoxia
regulation of transcription from RNA polymerase II promoter in response to hypoxia (GO:0061418) [BFO:0000050 relation] BFO:0000050  cellular response to hypoxia
positive regulation of cellular response to hypoxia (GO:1900039) [RO:0002213 relation] RO:0002213  cellular response to hypoxia
regulation of cellular response to hypoxia (GO:1900037) [RO:0002211 relation] RO:0002211  cellular response to hypoxia
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