3-hydroxymethylcephem carbamoyltransferase

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3-hydroxymethylcephem carbamoyltransferase
Identifiers
EC number2.1.3.7
CAS number74315-96-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a 3-hydroxymethylcephem carbamoyltransferase (EC 2.1.3.7) is an enzyme that catalyzes the chemical reaction

carbamoyl phosphate + a 3-hydroxymethylceph-3-em-4-carboxylate phosphate + a 3-carbamoyloxymethylcephem

Thus, the two substrates of this enzyme are carbamoyl phosphate and 3-hydroxymethylceph-3-em-4-carboxylate, whereas its two products are phosphate and 3-carbamoyloxymethylcephem.

This enzyme belongs to the family of transferases that transfer one-carbon groups, specifically the carboxy- and carbamoyltransferases. The systematic name of this enzyme class is carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate carbamoyltransferase. This enzyme has at least one effector, ATP.

References[edit]

  • Brewer SJ, Taylor PM, Turner MK (1980). "An adenosine triphosphate-dependent carbamoylphosphate--3-hydroxymethylcephem O-carbamoyltransferase from Streptomyces clavuligerus". Biochem. J. 185 (3): 555–64. PMC 1161431. PMID 6248024.