|CompTox Dashboard (EPA)|
|Chemical and physical data|
|Molar mass||214.61 g/mol g·mol−1|
|3D model (JSmol)|
|NY (what is this?)|
8-Chlorotheophylline, also known as 1,3-dimethyl-8-chloroxanthine, is a stimulant drug of the xanthine chemical class, with physiological effects similar to caffeine. Its main use is in combination (salt) with diphenhydramine in the antiemetic dimenhydrinate. Diphenhydramine reduces nausea but causes drowsiness, and the stimulant properties of 8-Chlorotheophylline help ward off that side-effect.
- S H Snyder; J J Katims; Z Annau; R F Bruns & J W Daly (May 1, 1981). "Adenosine receptors and behavioral actions of methylxanthines". PNAS. 78: 3260–3264. doi:10.1073/pnas.78.5.3260. PMC 319541.
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