Analgesic adjuvant

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An analgesic adjuvant is a medication that is typically used for indications other than pain control but provides control of pain in some painful diseases. Anti-emetics and medication to relieve constipation are two examples of non-adjuvant medication indications because these are used to treat side effects and adverse effects.[1] Examples include:

The exact mechanism of carbamazepine, gabapentin, and pregabalin is similarly unclear, but these anticonvulsants are used to treat neuropathic pain with differing degrees of success.[4]


  1. ^ "WHO Guidelines on the Pharmacological Treatment of Persisting Pain in Children with Medical Illnesses" (PDF). World Health Organization. 2012. Retrieved 21 August 2017.
  2. ^ Bryson, HM; Wilde, MI (1 June 1996). "Amitriptyline. A review of its pharmacological properties and therapeutic use in chronic pain states". Drugs & Aging. 8 (6): 459–476. PMID 8736630.
  3. ^ Elliott, KJ; Brodsky, M; Hynansky, A; Foley, KM; Inturrisi, CE. Dextromethorphan shows efficacy in experimental pain (nociception) and opioid tolerance. NEUROLOGY, 2005.
  4. ^ Eardley, I; Whelan, P; Kirby, R; Schaeffer, A. "Drugs Used In The Treatment Of Interstitial Cystitis". Drug Treatment in Urology. John Wiley & Sons, 2008. p. 65.

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