Azapride

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Azapride
Azapride.png
Clinical data
SynonymsAzidoclebopride
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H22ClN5O2
Molar mass399.88 g·mol−1
3D model (JSmol)
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Azapride is the azide derivative of the dopamine antagonist clebopride synthesized in order to label dopamine receptors.[1][2] It is an irreversible dopamine antagonist.[2]

References[edit]

  1. ^ Niznik, H. B; Guan, J. H; Neumeyer, J. L; Seeman, P (1985). "A photoaffinity ligand for dopamine D2 receptors: Azidoclebopride". Molecular Pharmacology. 27 (2): 193–9. PMID 3969068.
  2. ^ a b Wouters, W; Van Dun, J; Laduron, P. M (1984). "Photoaffinity labelling of dopamine receptors. Synthesis and binding characteristics of azapride". European Journal of Biochemistry. 145 (2): 273–8. PMID 6548707.