3-Cyclopentylpropionic acid; 3-Cyclopentanepropionic acid; Cypionate; Cipionate
3D model (JSmol)
CompTox Dashboard (EPA)
|Molar mass||142.198 g·mol−1|
|Melting point||130 to 132 °C (266 to 270 °F; 403 to 405 K) (12 mmHg)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
The primary use of cypionic acid is in pharmaceutical formulations. Cypionic acid is used to prepare ester prodrugs which have increased half-lives relative to the parent compound. The lipophilicity of the cypionate group allows the prodrug to be sequestered in fat depots after intramuscular injection. The ester group is slowly hydrolyzed by metabolic enzymes, releasing steady doses of the active ingredient. Examples include testosterone cypionate, estradiol cypionate, hydrocortisone cypionate, oxabolone cipionate, and mesterolone cypionate.