DBP (gene)

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DBP
Identifiers
AliasesDBP, DABP, D-box binding PAR bZIP transcription factor, taxREB302
External IDsMGI: 94866 HomoloGene: 1035 GeneCards: DBP
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for DBP
Genomic location for DBP
Band19q13.33Start48,630,030 bp[1]
End48,637,438 bp[1]
RNA expression pattern
PBB GE DBP 209783 at fs.png

PBB GE DBP 209782 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001352

NM_016974

RefSeq (protein)

NP_001343

NP_058670

Location (UCSC)Chr 19: 48.63 – 48.64 MbChr 7: 45.71 – 45.71 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

D site of albumin promoter (albumin D-box) binding protein, also known as DBP, is a protein which in humans is encoded by the DBP gene.[5][6]

DBP is a member of the PAR bZIP (Proline and Acidic amino acid-Rich basic leucine ZIPper) transcription factor family.[5][7] DBP binds to an upstream promoter in the insulin gene.[8]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000105516 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000059824 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ a b "Entrez Gene: DBP D site of albumin promoter (albumin D-box) binding protein".
  6. ^ Szpirer C, Riviere M, Cortese R, Nakamura T, Islam MQ, Levan G, Szpirer J (Jun 1992). "Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)". Genomics. 13 (2): 293–300. doi:10.1016/0888-7543(92)90245-N. PMID 1535333.
  7. ^ Khatib ZA, Inaba T, Valentine M, Look AT (Sep 1994). "Chromosomal localization and cDNA cloning of the human DBP and TEF genes". Genomics. 23 (2): 344–51. doi:10.1006/geno.1994.1510. PMID 7835883.
  8. ^ Melloul D, Marshak S, Cerasi E (Mar 2002). "Regulation of insulin gene transcription". Diabetologia. 45 (3): 309–26. doi:10.1007/s00125-001-0728-y. PMID 11914736.

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.