Dipeptidase 3

From Wikipedia, the free encyclopedia
  (Redirected from DPEP3)
Jump to navigation Jump to search
DPEP3
Identifiers
AliasesDPEP3, MBD3, dipeptidase 3
External IDsMGI: 1919104 HomoloGene: 23357 GeneCards: DPEP3
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for DPEP3
Genomic location for DPEP3
Band16q22.1Start67,975,663 bp[1]
End67,980,508 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_022357
NM_001129758
NM_001370198

NM_027960

RefSeq (protein)

NP_001123230
NP_071752
NP_001357127

NP_082236

Location (UCSC)Chr 16: 67.98 – 67.98 MbChr 8: 105.97 – 105.98 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Dipeptidase 3 (DPEP3) is a protein that in humans is encoded by the DPEP3 gene.[5]

This gene encodes a membrane-bound glycoprotein from the family of dipeptidases (EC 3.4.13.19) involved in hydrolytic metabolism of various dipeptides, including penem and carbapenem beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family, DPEP2. Alternatively spliced transcript variants that encode different isoforms have been found for this gene.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000141096 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031898 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Habib GM, Shi ZZ, Cuevas AA, Lieberman MW (July 2003). "Identification of two additional members of the membrane-bound dipeptidase family". The FASEB Journal. 17 (10): 1313–5. doi:10.1096/fj.02-0899fje. PMID 12738806.
  6. ^ "Entrez Gene: Dipeptidase 3".

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.