Ezekiel Holmes (August 21, 1801 – February 9, 1865) was an American agriculturalist and politician known as the "father of Maine agriculture". Holmes secured the establishment of the University of Maine as an independent institution located in Orono, Maine.
Holmes served four consecutive single-year terms in the Maine House of Representatives from 1836 to 1840. He served two single year terms in the Maine Senate in 1844 and 1845 before returning to the House for two terms in 1851 and 1852. He was the nominee of the Liberty Party for governor in 1853 and 1854. He lost to Whig William G. Crosby both times.
- Bailey, Liberty Hyde; Miller, Wilhelm (1909). Cyclopedia of American Horticulture: R-Z. Macmillan. pp. 365–. Retrieved 1 August 2015.
- Ezekiel Holmes: Father of Maine Agriculture by Clarence A. Day, University of Maine Press
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