FOXK2

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FOXK2
Protein FOXK2 PDB 1jxs.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFOXK2, ILF, ILF-1, ILF1, forkhead box K2, nGTBP
External IDsOMIM: 147685 MGI: 1916087 HomoloGene: 18748 GeneCards: FOXK2
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for FOXK2
Genomic location for FOXK2
Band17q25.3Start82,519,713 bp[1]
End82,644,662 bp[1]
RNA expression pattern
PBB GE FOXK2 203064 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004514
NM_181430
NM_181431

NM_001080932
NM_001363033

RefSeq (protein)

NP_004505

NP_001074401
NP_001349962

Location (UCSC)Chr 17: 82.52 – 82.64 MbChr 11: 121.26 – 121.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Forkhead box protein K2 is a protein that in humans is encoded by the FOXK2 gene.[5][6]

The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000141568 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039275 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Durand DB, Shaw JP, Bush MR, Replogle RE, Belagaje R, Crabtree GR (Jul 1988). "Characterization of antigen receptor response elements within the interleukin-2 enhancer". Mol Cell Biol. 8 (4): 1715–24. PMC 363332. PMID 3260003.
  6. ^ a b "Entrez Gene: FOXK2 forkhead box K2".

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.