GJA10

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GJA10
Identifiers
AliasesGJA10, CX62, gap junction protein alpha 10
External IDsOMIM: 611924 MGI: 1339969 HomoloGene: 7733 GeneCards: GJA10
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for GJA10
Genomic location for GJA10
Band6q15Start89,894,469 bp[1]
End89,921,760 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_032602

NM_010289

RefSeq (protein)

NP_115991

NP_034419

Location (UCSC)Chr 6: 89.89 – 89.92 MbChr 4: 32.6 – 32.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Gap junction alpha-10 protein, also known as connexin-62 (Cx62), is a protein that in humans is encoded by the GJA10 gene.[5]

Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[5][6]

References[edit]

  1. ^ a b c ENSG00000288435 GRCh38: Ensembl release 89: ENSG00000135355, ENSG00000288435 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000051056 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: gap junction protein".
  6. ^ Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038.

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.