HOXA4

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HOXA4
Identifiers
AliasesHOXA4, HOX1, HOX1D, homeobox A4
External IDsOMIM: 142953 MGI: 96176 HomoloGene: 37583 GeneCards: HOXA4
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for HOXA4
Genomic location for HOXA4
Band7p15.2Start27,128,507 bp[1]
End27,130,799 bp[1]
RNA expression pattern
PBB GE HOXA4 206289 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002141

NM_008265

RefSeq (protein)

NP_002132

NP_032291

Location (UCSC)Chr 7: 27.13 – 27.13 MbChr 6: 52.19 – 52.19 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Homeobox A4, also known as HOXA4, is a protein which in humans is encoded by the HOXA4 gene.[5][6]

Function[edit]

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes.[7] Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.[5]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000197576 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000000942 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ a b "Entrez Gene: HOXA4 homeobox A4".
  6. ^ McAlpine PJ, Shows TB (July 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
  7. ^ Scott MP (November 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459.

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.