Imidazol-4-one-5-propionic acid

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Imidazol-4-one-5-propionic acid
Imidazol-4-one-5-propionic acid.png
IUPAC name
3-(5-Oxo-1,4-dihydroimidazol-4-yl)propanoic acid
3D model (JSmol)
MeSH Imidazol-4-one-5-propionic+acid
Molar mass 156.139
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Imidazol-4-one-5-propionic acid is an intermediate in the metabolism of histidine. It is a colorless compound that is sensitive to light in air. The compound features an imidazolone ring.[1] It arises via the action of urocanase on urocanic acid. Hydrolysis of the heterocycle to the glutamic acid derivative is catalyzed by imidazolonepropionate hydrolase.

See also[edit]


  1. ^ Hassall, H.; Greenberg, D. M. (1971). "Preparation and properties of 4(5)-imidazolone-5(4)-propionic acid". Methods Enzymol. 17(Pt. B): 89–91. doi:10.1016/0076-6879(71)17014-0.