Interleukin-28 receptor

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interleukin 28 receptor, alpha (interferon, lambda receptor)
Identifiers
SymbolIL28RA
Alt. symbolsCRF2/12, IFNLR, IL-28R1
NCBI gene163702
HGNC18584
OMIM607404
RefSeqNM_170743
UniProtQ8IU57
Other data
LocusChr. 1 p36.11
interleukin 10 receptor, beta
Identifiers
SymbolIL10RB
Alt. symbolsCRFB4, D21S58, D21S66
NCBI gene3588
HGNC5965
OMIM123889
RefSeqNM_000628
UniProtQ08334
Other data
LocusChr. 21 q22.1-22.2

Interleukin-28 receptor is a type II cytokine receptor. It binds interleukin-28. It consists of an α and shares a common β subunit with the interleukin-10 receptor.[1][2]

References[edit]

  1. ^ Kotenko SV, Gallagher G, Baurin VV, Lewis-Antes A, Shen M, Shah NK, Langer JA, Sheikh F, Dickensheets H, Donnelly RP (2003). "IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex". Nat. Immunol. 4 (1): 69–77. doi:10.1038/ni875. PMID 12483210.
  2. ^ Sheppard P, Kindsvogel W, Xu W, Henderson K, Schlutsmeyer S, Whitmore TE, Kuestner R, Garrigues U, Birks C, Roraback J, Ostrander C, Dong D, Shin J, Presnell S, Fox B, Haldeman B, Cooper E, Taft D, Gilbert T, Grant FJ, Tackett M, Krivan W, McKnight G, Clegg C, Foster D, Klucher KM (2003). "IL-28, IL-29 and their class II cytokine receptor IL-28R". Nat. Immunol. 4 (1): 63–8. doi:10.1038/ni873. PMID 12469119.

External links[edit]