Ipsapirone

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Ipsapirone
Ipsapirone.svg
Clinical data
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Pharmacokinetic data
Elimination half-life1.3-2.7 hours
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H23N5O3S
Molar mass401.484 g/mol g·mol−1
3D model (JSmol)
  (verify)

Ipsapirone is a selective 5-HT1A receptor partial agonist of the piperazine and azapirone chemical classes.[1] It has antidepressant and anxiolytic effects.[1] Ipsapirone was studied in several placebo-controlled trials for depression and continues to be used in research.[2]

See also[edit]

References[edit]

  1. ^ a b Fanelli RJ, Schuurman T, Glaser T, Traber J (1990). "Ipsapirone: a novel anxiolytic and selective 5-HT1A receptor ligand". Progress in clinical and biological research. 361: 461–7. PMID 1981264.
  2. ^ "Azapirones for generalized anxiety disorder". Cochrane Database Syst Rev (3): CD006115. Jul 19, 2006. doi:10.1002/14651858.CD006115. PMID 16856115.