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AliasesKCNV1, HNKA, KCNB3, KV2.3, KV8.1, potassium voltage-gated channel modifier subfamily V member 1
External IDsOMIM: 608164 MGI: 1914748 HomoloGene: 22811 GeneCards: KCNV1
Gene location (Human)
Chromosome 8 (human)
Chr.Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for KCNV1
Genomic location for KCNV1
Band8q23.2Start109,963,636 bp[1]
End109,975,771 bp[1]
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC)Chr 8: 109.96 – 109.98 MbChr 15: 45.11 – 45.11 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

Potassium voltage-gated channel subfamily V member 1 is a protein that in humans is encoded by the KCNV1 gene.[5][6] The protein encoded by this gene is a voltage-gated potassium channel subunit.[5][6]

Common variations in the KCNV1 gene have been associated with schizophrenia.[7]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164794 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022342 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Hugnot JP, Salinas M, Lesage F, Guillemare E, de Weille J, Heurteaux C, Mattei MG, Lazdunski M (Aug 1996). "Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels". EMBO J. 15 (13): 3322–31. doi:10.1002/j.1460-2075.1996.tb00697.x. PMC 451895. PMID 8670833.
  6. ^ a b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104.
  7. ^ Schizophrenia Working Group of the Psychiatric Genomics Consortium (2014-07-24). "Biological insights from 108 schizophrenia-associated genetic loci". Nature. 511 (7510): 421–427. doi:10.1038/nature13595. ISSN 1476-4687. PMC 4112379. PMID 25056061.

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