KLF8

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KLF8
Identifiers
AliasesKLF8, BKLF3, ZNF741, Kruppel-like factor 8, Kruppel like factor 8
External IDsOMIM: 300286 MGI: 2442430 HomoloGene: 68549 GeneCards: KLF8
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for KLF8
Genomic location for KLF8
BandXp11.21Start56,232,356 bp[1]
End56,291,531 bp[1]
RNA expression pattern
PBB GE KLF8 219930 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_173780
NM_001357183

RefSeq (protein)

NP_776141
NP_001344112

Location (UCSC)Chr X: 56.23 – 56.29 MbChr X: 153.24 – 153.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Krueppel-like factor 8 is a protein that in humans is encoded by the KLF8 gene.[5] KLF8 belongs to the family of KLF protein. KLF8 is activated by KLF1 along with KLF3 while KLF3 represses KLF8.[6]

Interactions[edit]

KLF8 has been shown to interact with CTBP2.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000102349 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041649 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ "Entrez Gene: KLF8 Kruppel-like factor 8".
  6. ^ Alister P. W. Funnell; et al. "Generation of Mice Deficient in both KLF3/BKLF and KLF8 Reveals a Genetic Interaction and a Role for These Factors in Embryonic Globin Gene Silencing". asm.org. Retrieved 12 January 2019.
  7. ^ van Vliet J, Turner J, Crossley M (May 2000). "Human Krüppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription". Nucleic Acids Research. 28 (9): 1955–62. doi:10.1093/nar/28.9.1955. PMC 103308. PMID 10756197.

Further reading[edit]

External links[edit]