List of psychedelic drugs

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The following is a list of psychedelic drugs of various classes. Serotonergic psychedelics are usually considered to be the classical psychedelics, whereby the other classes are often only considered to have secondary psychedelic properties. Some of these compounds may be classified differently or under several categories, due to unique structural classification, multiple mechanisms of action, or to the fact that the precise pharmacodynamic actions of psychedelic drugs are not yet completely understood. Also, due to the vast amount of possible substitutions and analogs of psychedelic compounds, their total number is quite large and is not fully reflected within this list, leaving room for many that have not yet been sufficiently investigated and even others that have not yet been discovered.

Entries marked with a '#' are naturally occurring compounds.

Serotonergic psychedelics (serotonin 5-HT2A receptor agonists)[edit]

Empathogens/entactogens (serotonin (5-HT) releasing agents)[edit]

Dissociatives (NMDA receptor antagonists)[edit]

Cannabinoids (CB-1 cannabinoid receptor ligands)[edit]


See also[edit]


  1. ^ Pertwee, R G (April 2006). "The pharmacology of cannabinoid receptors and their ligands: an overview". International Journal of Obesity. 30 (S1): S13–S18. doi:10.1038/sj.ijo.0803272. ISSN 0307-0565. PMID 16570099.
  2. ^ Cannabis and cannabinoids : pharmacology, toxicology, and therapeutic potential. Grotenhermen, Franjo., Russo, Ethan. New York: Haworth Integrative Healing Press. 2002. ISBN 9781136614941. OCLC 606854125.CS1 maint: others (link)
  3. ^ Huestis, M. A. (2005), "Pharmacokinetics and Metabolism of the Plant Cannabinoids, Δ9-Tetrahydrocannibinol, Cannabidiol and Cannabinol", in Pertwee, Roger G. (ed.), Cannabinoids, Handbook of Experimental Pharmacology, 168, Springer-Verlag, pp. 657–690, doi:10.1007/3-540-26573-2_23, ISBN 9783540225652
  4. ^ Laprairie, R B; Bagher, A M; Kelly, M E M; Denovan‐Wright, E M (October 2015). "Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor". British Journal of Pharmacology. 172 (20): 4790–4805. doi:10.1111/bph.13250. ISSN 0007-1188. PMC 4621983. PMID 26218440.