MYT1

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search

MYT1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMYT1, C20orf36, MTF1, MYTI, NZF2, PLPB1, ZC2HC4A, ZC2H2C1, myelin transcription factor 1
External IDsOMIM: 600379 MGI: 1100535 HomoloGene: 3332 GeneCards: MYT1
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for MYT1
Genomic location for MYT1
Band20q13.33Start64,102,394 bp[1]
End64,242,253 bp[1]
RNA expression pattern
PBB GE MYT1 210341 at fs.png

PBB GE MYT1 215822 x at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004535

NM_001171615
NM_001171616
NM_001171680
NM_008665

RefSeq (protein)

NP_004526

NP_001165086
NP_001165087
NP_001165151
NP_032691

Location (UCSC)Chr 20: 64.1 – 64.24 MbChr 2: 181.76 – 181.83 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Myelin transcription factor 1 is a protein that in humans is encoded by the MYT1 gene.[5][6][7]

Function[edit]

The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.[7]

Interactive pathway map[edit]

Click on genes, proteins and metabolites below to visit related articles. [§ 1]

[[File:
MECP2_and_Associated_Rett_Syndrome_WP3584Go to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to Entrez GeneGo to WikiPathwaysGo to articleGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to articleGo to Entrez GeneGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to Entrez GeneGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to Entrez GeneGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to article
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
MECP2_and_Associated_Rett_Syndrome_WP3584Go to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to Entrez GeneGo to WikiPathwaysGo to articleGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to articleGo to Entrez GeneGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to miRBaseGo to Entrez GeneGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to Entrez GeneGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to articleGo to article
|{{{bSize}}}px|alt=MECP2 and associated Rett Syndrome edit]]
MECP2 and associated Rett Syndrome edit
  1. ^ The interactive pathway map can be edited at WikiPathways: "WP3584".

Interactions[edit]

MYT1 has been shown to interact with PIN1.[8]

References[edit]

  1. ^ a b c ENSG00000276876 GRCh38: Ensembl release 89: ENSG00000196132, ENSG00000276876 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000010505 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kim JG, Hudson LD (December 1992). "Novel member of the zinc finger superfamily: A C2-HC finger that recognizes a glia-specific gene". Molecular and Cellular Biology. 12 (12): 5632–9. doi:10.1128/mcb.12.12.5632. PMC 360502. PMID 1280325.
  6. ^ Booher RN, Holman PS, Fattaey A (August 1997). "Human Myt1 is a cell cycle-regulated kinase that inhibits Cdc2 but not Cdk2 activity". The Journal of Biological Chemistry. 272 (35): 22300–6. doi:10.1074/jbc.272.35.22300. PMID 9268380.
  7. ^ a b "Entrez Gene: MYT1 myelin transcription factor 1".
  8. ^ Wells NJ, Watanabe N, Tokusumi T, Jiang W, Verdecia MA, Hunter T (October 1999). "The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression". Journal of Cell Science. 112 (19): 3361–71. PMID 10504341.

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.