At age 13, she was a soloist with the Detroit Symphony Orchestra. At age 20, she won the Walter W. Naumburg Foundation International Piano Competition. Her concert career included soloing with many major symphony orchestras and took her to venues around the globe. In 1994, she became the first American artist to perform in Vietnam after the Vietnam War. The government of Vietnam invited her back on several occasions to perform. A staunch supporter of the arts in her local community of Akron, Ohio, as well as internationally, she was a professor emeritus at Kent State University, where she taught piano for 25 years. She was married to Earl Baxtresser, with whom she raised two sons, two daughters, and two adopted daughters. Her eldest daughter is flutist Jeanne Baxtresser.
- "Margaret Baxtresser: A life In Tune". Archived from the original on 2006-12-05. Retrieved 2007-03-15.
- "In Performance To Pay Tribute To Margaret Baxtresser". Archived from the original on 2007-09-28. Retrieved 2007-03-15.