Pituitary disease

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Pituitary disease
SpecialtyEndocrinology Edit this on Wikidata

A pituitary disease is a disorder primarily affecting the pituitary gland.[1]

The main disorders involving the pituitary gland are:

Condition Direction Hormone
Acromegaly overproduction growth hormone
Cushing's disease overproduction adrenocorticotropic hormone
Growth hormone deficiency underproduction growth hormone
Syndrome of inappropriate antidiuretic hormone overproduction vasopressin
Diabetes insipidus
(can also be nephrogenic)
underproduction vasopressin
Sheehan syndrome underproduction any pituitary hormone
Pickardt-Fahlbusch Syndrome underproduction any pituitary hormone, except prolactin, which is increased
Hyperpituitarism (most commonly pituitary adenoma) overproduction any pituitary hormone
Hypopituitarism underproduction any pituitary hormone

Overproduction or underproduction of a pituitary hormone will affect the respective end-organ. For example, insufficient production (hyposecretion) of thyroid stimulating hormone (TSH) in the pituitary gland will cause hypothyroidism, while overproduction (hypersecretion) of TSH will cause hyperthyroidism. Thyroidisms caused by the pituitary gland are less common though, accounting for less than 10% of all hypothyroidism cases and much less than 1% of hyperthyroidism cases.[2][3]

See also[edit]


  1. ^ "Overview of the Pituitary Gland: Pituitary Gland Disorders: Merck Manual Home Health Handbook". Retrieved 2009-04-04.
  2. ^ Page 358 in: Aminoff, Michael J. (2007). Neurology and General Medicine: Expert Consult: Online and Print. Edinburgh: Churchill Livingstone. ISBN 978-0-443-06707-5.
  3. ^ Thyrotropin (TSH)-secreting pituitary adenomas. By Roy E Weiss and Samuel Refetoff. Last literature review version 19.1: January 2011. This topic last updated: July 2, 2009

External links[edit]