Prolactin-releasing peptide receptor

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PRLHR
Identifiers
AliasesPRLHR, GPR10, GR3, PrRPR, prolactin releasing hormone receptor
External IDsOMIM: 600895 MGI: 2135956 HomoloGene: 3134 GeneCards: PRLHR
Gene location (Human)
Chromosome 10 (human)
Chr.Chromosome 10 (human)[1]
Chromosome 10 (human)
Genomic location for PRLHR
Genomic location for PRLHR
Band10q26.11Start118,589,997 bp[1]
End118,595,648 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004248

NM_201615

RefSeq (protein)

NP_004239

NP_963909

Location (UCSC)Chr 10: 118.59 – 118.6 MbChr 19: 60.47 – 60.47 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The prolactin-releasing peptide receptor (PrRPR) also known as G-protein coupled receptor 10 (GPR10) is a protein that in humans is encoded by the PRLHR gene.

PrRPR is a G-protein coupled receptor[5] that binds the prolactin-releasing peptide (PRLH).[6]

Function[edit]

PrRPR is a 7-transmembrane domain receptor for prolactin-releasing peptide that is highly expressed in the anterior pituitary.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000119973 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045052 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Marchese A, Heiber M, Nguyen T, Heng HH, Saldivia VR, Cheng R, Murphy PM, Tsui LC, Shi X, Gregor P (1995). "Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors". Genomics. 29 (2): 335–44. doi:10.1006/geno.1995.9996. PMID 8666380.
  6. ^ Hinuma S, Habata Y, Fujii R, Kawamata Y, Hosoya M, Fukusumi S, Kitada C, Masuo Y, Asano T, Matsumoto H, Sekiguchi M, Kurokawa T, Nishimura O, Onda H, Fujino M (1998). "A prolactin-releasing peptide in the brain". Nature. 393 (6682): 272–6. doi:10.1038/30515. PMID 9607765.
  7. ^ "Entrez Gene: PRLHR prolactin releasing hormone receptor".

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.