RTI-352

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RTI-352
RTI-352.svg
Names
Other names
RTI-4229-352
Identifiers
3D model (JSmol)
Properties
C16H20INO2
Molar mass 385.245 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

RTI-352 is a phenyltropane that is used as a radiolabeling ligand for the DAT.[1]

RTI-352 is a geometric isomer of RTI-55 (β-CIT).[2]

Based on X-ray crystallography, this compound is in a tautomeric equilibrium residing mostly on the side of the boat-shaped conformer.

References[edit]

  1. ^ U.S. Patent 6,358,492
  2. ^ Zhan, Yougen; Saindane, Amit M.; Scheffel, Ursula; Carroll, F. Ivy; Holmquist, Christopher R.; Kepler, John A.; Taylor, George F.; Kuhar, Michael J. (1997). "RTI-352: A 3α Analogue of RTI-55 as an in vivo dopamine transporter binding ligand". Synapse. 25 (4): 389–392. doi:10.1002/(SICI)1098-2396(199704)25:4<389::AID-SYN10>3.0.CO;2-Q.