Roger S. Goody
Roger Goody at the Royal Society admissions day in London, July 2018
Roger Sidney Goody
April 17, 1944
|Alma mater||University of Birmingham (PhD)|
Max Planck Prize
German Academy of Sciences Leopoldina
Max Bergmann Medal
Fellow of the Royal Society
|Institutions||Memorial Sloan-Kettering Cancer Center|
Max Planck Institute of Molecular Physiology
|Thesis||Studies on the chemistry of cytosine and its derivatives (1968)|
Roger Sidney Goody FRS (17 April 1944 in Northampton) is an English biochemist who served as director at the Max Planck Institute for Molecular Physiology in Dortmund from 1993 until 2013. Since 2013 he is Emeritus Director of the institute.
Career and research
After his PhD, Goody was appointed a postdoctoral researcher at the Memorial Sloan-Kettering Cancer Center in New York City, NY, USA in the field of natural products research. In 1970 he became a scientific fellow at the Max Planck Institute for Experimental Medicine, Göttingen in the field of nucleotide research. From 1972 till 1993 he was a group leader at the Max Planck Institute for Medical Research, Heidelberg in the field of enzymology and nucleotide research, with a focus on actin, myosin, adenylate kinase, EF-Tu, HRAS-p21, reverse transcriptase, nucleotides and nucleic acid sequencing. An overriding theme of his research interests has been the transient states of enzymes, along the enzyme reaction pathway, against the background of selective and specific ligand-protein interactions and structure-function relationships. In 1983 he habilitated at the faculty for biochemistry and biophysics of the University of Heidelberg and was announced adjunct professor in 1990. In 1993 he accepted the position of Director at the Max Planck Institute for Molecular Physiology, Dortmund and became a scientific fellow of the Max Planck Society. Since 2004 Roger Goody has also held a full professorship in biochemistry (supramolecular systems) at the Ruhr University Bochum, with a dual emphasis on higher education and fundamental research.
Roger Goody has combined chemistry, structural biology and kinetics to make major contributions in several fields of biology. He pioneered the use of nucleotide analogs, synthesized at the beginning of his career, in muscle research and later for Ras-family GTPases, leading to the first ever structure determination of an unstable protein-substrate complex (Ras:GTP). Innovative use of semi-synthetic proteins led to an understanding of transport mechanisms of Rab GTPases and to resolution of a longstanding controversy concerning targeting of these proteins to membranes. His group discovered and characterized hitherto unrecognized covalent modifications of Rab proteins by bacteria.
Honours, awards and memberships
- President of the German Society of Biochemistry and molecular Biology
- German Academy of Sciences Leopoldina (since 2003)
- Max Bergman Society
- Awarded membership of the European Molecular Biology Organization (EMBO)
- Member of the Scientific Advisory Board of the Max Delbrück Center for Molecular Medicine (MDC) Berlin Buch
- Chairman of the Study Section for Biochemistry, Biophysics and Structural Biology of the Deutsche Forschungsgemeinschaft (German National Research Organization) - 2000-2009
- 1991: Max Planck Prize
- 2003: German Academy of Sciences Leopoldina
- 2008: Max Bergmann Medal
- 2012: Astbury Lecture - Astbury Society, Leeds
- 2012: Xu Guangqi Lecture, CAS-Max-Planck Partner Institute, Shanghai China
- 2015: Feldberg Prize
- 2018: Elected Fellow of the Royal Society (FRS)
Goody is married and has two children.
- Goody, Roger Sidney (1968). Studies on the chemistry of cytosine and its derivatives. bham.ac.uk (PhD thesis). University of Birmingham. OCLC 911166913. Copac 45170305.
- "Goody, Roger S". www.mpg.de.
- "Vorlesungsverzeichnis SS 2018". www.uv.ruhr-uni-bochum.de.
- "GBM-Startseite - Homepage der Gesellschaft für Biochemie und Molekularbiologie e.V". www.gbm-online.de.
- "Find people in the EMBO Communities". people.embo.org.
- "List of Members". websrv.leopoldina.org.
- "Distinguished scientists elected as Fellows and Foreign Members of the Royal Society". royalsociety.org.
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