Sensitization (immunology)

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In immunology, the term sensitization is used for the following concepts:[1][2][3][4][5]

Those particles themselves are biologically inactive except for serving as antigens against the primary antibodies or as carriers of the antigens.[5] When antibodies are used in the preparation, they are bound to the erythrocyte or particles in their Fab regions. Thus the step follows requires the secondary antibodies against those primary antibodies, that is, the secondary antibodies must have binding specificity to the primary antibodies including to their Fc regions.


  1. ^ a b c Anderson DM, ed. (2003). "Sensitization." Dorland's Illustrated Medical Dictionary, 30th ed. Philadelphia: Saunders, p. 1680. ISBN 0-7216-0146-4.
  2. ^ a b c Brown MJ, ed. (1992). "Sensitization." Miller-Keane Encyclopedia & Dictionary of Medicine, Nursing, and Allied Health, 5th ed. Philadelphia; London: Saunders, p. 1352. ISBN 0-7216-3456-7.
  3. ^ a b Pugh MB, ed. (2000). "Sensitization." Stedman's Medical Dictionary, 27th ed. Philadelphia: Lippincott Williams and Wilkins, p. 1619. ISBN 0-683-40007-X.
  4. ^ a b c Janeway C, Travers P, Walport M, Shlomchik M, eds. (2001). Immunobiology 5: The Immune System in Health and Disease. New York: Garland Pub., ISBN 0-8153-3642-X
  5. ^ a b c d e Tada T, Taniguchi M, Okumura Y, Miyasaka M, eds. (1993). "Sensitization." Dictionary of Terms in Immunology, 3rd ed. Osaka: Saishin-Igakusha, Ltd., p. 510. ISBN 4-914909-10-3 C3547 (in Japanese).