TAS2R13

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TAS2R13
Identifiers
AliasesTAS2R13, T2R13, TRB3, taste 2 receptor member 13
External IDsOMIM: 604792 MGI: 2681259 HomoloGene: 41542 GeneCards: TAS2R13
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for TAS2R13
Genomic location for TAS2R13
Band12p13.2Start10,907,926 bp[1]
End10,909,562 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_023920

NM_207024

RefSeq (protein)

NP_076409

NP_996907

Location (UCSC)Chr 12: 10.91 – 10.91 MbChr 6: 132.7 – 132.7 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Taste receptor type 2 member 13 is a protein that in humans is encoded by the TAS2R13 gene.[5][6][7]

Function[edit]

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.[7]

See also[edit]

References[edit]

  1. ^ a b c ENSG00000277254, ENSG00000273457 GRCh38: Ensembl release 89: ENSG00000212128, ENSG00000277254, ENSG00000273457 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000071150 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS (Apr 2000). "A novel family of mammalian taste receptors". Cell. 100 (6): 693–702. doi:10.1016/S0092-8674(00)80705-9. PMID 10761934.
  6. ^ Matsunami H, Montmayeur JP, Buck LB (Apr 2000). "A family of candidate taste receptors in human and mouse". Nature. 404 (6778): 601–4. doi:10.1038/35007072. PMID 10766242.
  7. ^ a b "Entrez Gene: TAS2R13 taste receptor, type 2, member 13".

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.