From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
TOX high mobility group box family member 2
Alt. symbolsC20orf100, GCX-1
NCBI gene84969
Other data
LocusChr. 20 q13.12

TOX high mobility group box family member 2, also known as TOX2, is a human gene.[1][2]

The protein encoded by this gene is a member of a subfamily of transcription factors that also includes TOX, TOX3, and TOX4 that share almost identical HMG-box DNA-binding domains which function to modify chromatin structure.[3]


  1. ^ "Entrez Gene: TOX high mobility group box family member 2".
  2. ^ Kajitani T, Mizutani T, Yamada K, Yazawa T, Sekiguchi T, Yoshino M, Kawata H, Miyamoto K (May 2004). "Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells". Endocrinology. 145 (5): 2307–18. doi:10.1210/en.2003-1343. PMID 14764631.
  3. ^ O'Flaherty E, Kaye J (April 2003). "TOX defines a conserved subfamily of HMG-box proteins". BMC Genomics. 4: 13. doi:10.1186/1471-2164-4-13. PMC 155677. PMID 12697058.