Tinyatoxin

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Tinyatoxin
Tinyatoxin.svg
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.165.094
MeSH tinyatoxin
Properties
C36H38O8
Molar mass 598.692 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Tinyatoxin
Hottest-chili-rating.gif
HeatAbove peak
Scoville scale5,300,000,000 SHU

Tinyatoxin (TTX or TTN) is an analog of the neurotoxin resiniferatoxin. It occurs naturally in Euphorbia poissonii.[1]

It is a neurotoxin that acts via full agonism of the vanilloid receptors of sensory nerves.[2] Tinyatoxin has a potential for pharmaceutical uses similar to uses of capsaicin. Tinyatoxin is about one third as strong as resiniferatoxin but is still an ultrapotent analogue of capsaicin, with a heat intensity estimate of 300 to 350 times that of capsaicin.[citation needed]

References[edit]

  1. ^ Euphorbia poissonii in BoDD – Botanical Dermatology Database
  2. ^ Szallasi, A. & Blumberg, P.M. (1991). "Characterization of vanilloid receptors in the dorsal horn of pig spinal cord". Brain Res. 547 (2): 335–338. doi:10.1016/0006-8993(91)90982-2. PMID 1884211.