Trichoepithelioma

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Trichoepithelioma
Other namesBrooke's tumour Epithelioma afenoides cysticum .
Trichoepithelioma - high mag.jpg
Micrograph of a trichoepithelioma. H&E stain.
SpecialtyDermatology
Usual onsetusually young adults
TreatmentAny suspicicion of malignant change calls for adequate excision and histological examination . The only other reason for treatment is cosmetic . Partial destruction is usally followed by regrowth . Many treatment modalities may be used including surgical excision , curettage , cryotherapy and dermabrasion . High energy pulsed carbon dioxide laser has also been advocated as a useful treatment .

Trichoepithelioma is a neoplasm of the adnexa of the skin.[1] Its appearance is similar to basal cell carcinoma.

One form has been mapped to chromosome 9p21.[2]

Types[edit]

Trichoepitheliomas may be divided into the following types:[3]:672

Pathology[edit]

Trichoepitheliomas consisted of nests of basaloid cells. They lack the myxoid stroma and artefactual clefting seen in basal cell carcinoma. Mitoses are uncommon when compared to basal cell carcinoma.

Diagnosis[edit]

See also[edit]

References[edit]

  1. ^ "Trichoepithelioma: Overview - eMedicine Dermatology". Retrieved 2009-02-11.
  2. ^ Salhi A, Bornholdt D, Oeffner F, et al. (August 2004). "Multiple familial trichoepithelioma caused by mutations in the cylindromatosis tumor suppressor gene". Cancer Res. 64 (15): 5113–7. doi:10.1158/0008-5472.CAN-04-0307. PMID 15289313.
  3. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.

External links[edit]

Classification