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3-chloropropionic acid.svg
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.003.214 Edit this at Wikidata
Chemical and physical data
Molar mass108.52 g/mol g·mol−1
3D model (JSmol)
Melting point42 °C (108 °F)
Boiling point204 °C (399 °F) (decomp.)

3-Chloropropanoic acid (also 3-chloropropionic acid) or UMB66 is a drug used in scientific research. It is structurally related to GHB and binds to the GHB receptor, but has no affinity for GABA receptors.[1] It is also an active ingredient in some herbicide blends.[2] Overdose may cause unconsciousness and/or convulsions.[3]


  1. ^ Macias, A. T.; Hernandez, R. J.; Mehta, A. K.; MacKerell, A. D. Jr; Ticku, M. K.; Coop, A. (2004). "3-Chloropropanoic acid (UMB66): A ligand for the gamma-hydroxybutyric acid receptor lacking a 4-hydroxyl group". Bioorganic & Medicinal Chemistry. 12 (7): 1643–1647. doi:10.1016/j.bmc.2004.01.025. PMID 15028257.
  2. ^ Ng, H. J.; Ab. Wahab, R.; Cooper, R. A.; Huyop, F. (2005). "Degradation Of Herbicide (3-Chloropropionic Acid) By Bacterial Dehalogenases" (PDF). Proc. KUSTEM 4th Annual Seminar 2005: 586–590. Archived from the original (pdf) on 2016-03-05. Cite uses deprecated parameter |deadurl= (help)
  3. ^ "Chemical Data Sheet for 3-CHLOROPROPIONIC ACID". NOAA.