The building is located at 500 Church Street. It was built in 1963 by Albert Kahn Associates, and stands twelve stories in height. It is a brick building with a modern style. Twelve floors are above-ground, and there is one basement floor. The high-rise is used mainly for undergraduate education, particularly physics and mathematics. The low-rise section contains a number of large lecture halls; the two sections are connected by a breezeway on the second floor. The building is also home to the astronomy and astrophysics department.
In 2015, Dennison was renamed to Weiser Hall.