Zirconium granuloma

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Zirconium granuloma
Granuloma mac.jpg
Histological image

Zirconium granulomas are a skin condition characterized by a papular eruption involving the axillae, and are sometimes considered an allergic reaction to deodorant containing zirconium lactate.[1]:46 They are the result of a delayed granulomatous hypersensitivity reaction, and can also occur from exposure to aluminum zirconium complexes. Commonly, zirconium containing products are used to relieve toxicodendron irritation. The lesions are similar to those from sarcoidosis, and commonly manifest four to six weeks after contact. They appear as erythematous, firm, raised, shiny papules. Corticosteroids are used to ease the inflammation, but curative treatment is currently unavailable.[2][3]

See also[edit]


  1. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  2. ^ P. Darbre. Aluminium, antiperspirants and breast cancer. Journal of Inorganic Biochemistry 99:9.
  3. ^ Fischer's Contact Dermatitis. R. Rietschel; J. Fowler. 2008.

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